CBD and Inflammation: What Research Tells Us

Sep 09, 2025Carrie Horn

CBD and Inflammation: What Research Tells Us

Cannabidiol (CBD) was first isolated in 1940, but for decades it was overshadowed by THC — the compound best known for cannabis’s psychoactive effects. Because CBD doesn’t create a “high,” its potential benefits were largely overlooked.

That’s changing. Research, including a review by Sumner Burstein (Bioorganic & Medicinal Chemistry, 2015), highlights CBD’s role in inflammation. Studies suggest CBD may influence:

  • Receptors tied to immune and inflammatory responses

  • Signaling pathways inside cells that regulate inflammation

  • Gene expression linked to inflammatory activity

While there’s still much to learn, CBD is increasingly recognized for its potential in managing inflammation — and for broadening how we think about cannabis beyond THC.

Find more information about this study here. 

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