CBD and Inflammation: What Research Tells Us
Inflammation

CBD and Inflammation: What Research Tells Us

For decades, cannabis research focused almost entirely on THC, leaving cannabidiol (CBD) in the background. That has shifted as studies now highlight CBD’s role in inflammation.
By Carrie Horn · September 9, 2025 · 1 min read

Cannabidiol (CBD) was first isolated in 1940, but for decades it was overshadowed by THC - the compound best known for cannabis’s psychoactive effects. Because CBD doesn’t create a “high,” its potential benefits were largely overlooked.

That’s changing. Research, including a review by Sumner Burstein (Bioorganic & Medicinal Chemistry, 2015), highlights CBD’s role in inflammation. Studies suggest CBD may influence:

  • Receptors tied to immune and inflammatory responses

  • Signaling pathways inside cells that regulate inflammation

  • Gene expression linked to inflammatory activity

While there’s still much to learn, CBD is increasingly recognized for its potential in managing inflammation — and for broadening how we think about cannabis beyond THC.


Find more information about this study here. 

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