Alcohol use disorder (AUD)

Alcohol use disorder is a medical condition marked by an impaired ability to stop or control drinking despite harmful consequences to health, relationships or responsibilities.

It spans a spectrum from mild to severe and is defined by patterns such as drinking more than intended, unsuccessful attempts to cut down, cravings, tolerance and withdrawal symptoms when alcohol is stopped. Genetics, early exposure, mental health conditions and social environment all contribute to risk. Long-term heavy drinking raises the likelihood of liver disease, cardiovascular problems, certain cancers and injury.

Clinicians diagnose the disorder through structured interviews based on established diagnostic criteria, often supported by screening questionnaires and laboratory markers. Evidence-based care includes behavioral therapies, mutual-support groups and several approved medications. Cannabidiol has been examined in preclinical models of alcohol-related behavior, but human evidence is sparse and no established role in care exists.